Graphene oxide pegylated as antimicrobial against skin infections

  1. Javier Pérez-Piñeiro 1
  2. Arisbel Cerpa-Naranjo 1
  3. María F. Gilsanz-Muñoz 1
  4. Rodrigo Blasco-Chicano 1
  5. Fernando Esperón Fajardo 1
  6. Mónica Martínez-Martínez 1
  7. Bárbara Martín-Maldonado 1
  1. 1 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

Actes:
nanoBioMed 2023

Editorial: NanoMed Spain

Any de publicació: 2023

Pàgines: 125-126

Congrés: nanoBioMed 2023 International Conference, 21-23 de noviembre, Barcelona 2023

Tipus: Aportació congrés

GOOGLE SCHOLAR

Resum

Since the discovery of penicillin, medicine has beendeveloped around the availability of antibiotics to fightinfections. However, the adaptive capacity ofbacteria and their rapid multiplication have led to theemergence of antimicrobial resistance (AMR) as asurvival mechanism, which represents the greatesthealth challenge nowadays. A study published in2018 by Upreti et al. revealed that 56.9% of skininfections were caused by Staphylococcus aureus [2].Staphylococcus aureus is a clear example of theresult of decades of indiscriminate antibiotic use andrepresents the connection between the treatment ofwounds or skin lesions with antibiotics andnosocomial infections associated with long-stayhospital patients [3]. This bacterium can enter thebloodstream leading to circulatory, respiratory, andeven bone infections, which is not only a skin problembut a potential systemic problem.

Referències bibliogràfiques

  • Bennett, J. W.; Chung, K. T, Advances in applied microbiology, 49 (2001), 163-184.
  • Upreti, N.; Rayamajhee, B.; Sherchan, S. P.; Choudhari, M. K.; Banjara, M. R., Antimicrobial Resistance & Infection Control, 7(1) (2018), 1- 10.
  • Bassetti, M.; Righi, E.; Vena, A.; Graziano, E.; Russo, A.; Peghin, M., Current opinion in critical care, 24(5) (2018), 385-393.
  • Murray, C.J.; Ikuta, K.S.; Sharara, F.; Swetschinski, L.; Aguilar; G.R., Gray, A.; Naghavi, M., The Lancet, 399 (10325) (2022), 629-655.
  • Cerpa-Naranjo, A.; Pérez-Piñeiro, J., NavajasChocarro, P.; Arce, M.; Lado-Touriño, I.; Barrios-Bermúdez, N.; Moreno, R.; RojasCervantes, M.L., Materials, 15 (2022), 3593.
  • Marroki, A.; Bousmaha-Marroki, L., Encyclopedia of Infection and Immunity, Elsevier. Vol. 4, (2022), 320-341.