ESCUELA DE ARQUITECTURA, INGENIERÍA Y DISEÑO
Facultad
Instituto de Química Médica
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Química Médica (9)
2017
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Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia
European Journal of Medicinal Chemistry, Vol. 130, pp. 60-72
2014
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Dibenzo[1,4,5]thiadiazepine: A hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases
European Journal of Medicinal Chemistry, Vol. 81, pp. 350-358
2013
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Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia
Neuropharmacology, Vol. 67, pp. 403-411
2011
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Multi-target novel neuroprotective compound ITH33/IQM9.21 inhibits calcium entry, calcium signals and exocytosis
Cell Calcium, Vol. 50, Núm. 4, pp. 359-369
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N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235
2010
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Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates
ChemMedChem, Vol. 5, Núm. 11, pp. 1855-1870
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Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases
European Journal of Medicinal Chemistry, Vol. 45, Núm. 12, pp. 6152-6158
2009
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Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease
Journal of Medicinal Chemistry, Vol. 52, Núm. 22, pp. 7249-7257
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Pyrano[3,2-c]quinoline - 6-chlorotacrine hybrids as a novel family of acetylcholinesterase-and β-amyloid-directed anti-Alzheimer compounds
Journal of Medicinal Chemistry, Vol. 52, Núm. 17, pp. 5365-5379