Medicina
DEPARTAMENTO
Ignacio
Torres Alemán
Publicaciones en las que colabora con Ignacio Torres Alemán (29)
2024
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A role for astrocytic insulin-like growth factor I receptors in the response to ischemic insult
Journal of Cerebral Blood Flow and Metabolism, Vol. 44, Núm. 6, pp. 970-984
2022
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Insulin and insulin-like growth factor-I receptors in astrocytes exert different effects on behavior and Alzheimers-like pathology
F1000Research, Vol. 11
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Insulin and insulin-like growth factor-I receptors in astrocytes exert different effects on behavior and Alzheimer´s-like pathology
F1000Research, Vol. 11, pp. 663
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Insulin-like growth factor I sensitization rejuvenates sleep patterns in old mice
GeroScience, Vol. 44, Núm. 4, pp. 2243-2257
2021
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Astrocytic IGF-IRs induce adenosine-mediated inhibitory downregulation and improve sensory discrimination
Journal of Neuroscience, Vol. 41, Núm. 22, pp. 4768-4781
2020
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Insulin-like growth factor I modulates sleep through hypothalamic orexin neurons
FASEB Journal, Vol. 34, Núm. 12, pp. 15975-15990
2019
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Cell-specific expression of insulin/insulin-like growth factor-I receptor hybrids in the mouse brain
Growth Hormone and IGF Research, Vol. 45, pp. 25-30
2018
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A network of insulin peptides regulate glucose uptake by astrocytes: Potential new druggable targets for brain hypometabolism
Neuropharmacology, Vol. 136, pp. 216-222
2017
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A role for astrocytes in cerebellar deficits in frataxin deficiency: Protection by insulin-like growth factor I
Molecular and Cellular Neuroscience, Vol. 80, pp. 100-110
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Circulating insulin-like growth factor i regulates its receptor in the brain of male mice
Endocrinology, Vol. 158, Núm. 2, pp. 349-355
2016
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Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability
Cell, Vol. 166, Núm. 4, pp. 867-880
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Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death
Journal of Alzheimer's Disease, Vol. 52, Núm. 4, pp. 1471-1478
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The insulin-like growth factor I receptor regulates glucose transport by astrocytes
GLIA, Vol. 64, Núm. 11, pp. 1962-1971
2013
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Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice
Translational Psychiatry, Vol. 3
2012
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Early brain amyloidosis in APP/PS1 mice with serum insulin-like growth factor-I deficiency
Neuroscience Letters, Vol. 509, Núm. 2, pp. 101-104
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Reduced brain insulin-like growth factor I function during aging
Molecular and Cellular Neuroscience, Vol. 49, Núm. 1, pp. 9-12
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Regulation of the phosphatase calcineurin by insulin-like growth factor i unveils a key role of astrocytes in Alzheimer's pathology
Molecular Psychiatry, Vol. 17, Núm. 7, pp. 705-718
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The many faces of insulin-like peptide signalling in the brain
Nature Reviews Neuroscience, Vol. 13, Núm. 4, pp. 225-239
2010
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Chapter 13: Insulin-Like Growth Factor i as a Disease-Modifying Therapy in Alzheimer's Dementia
RSC Drug Discovery Series (Royal Society of Chemistry), pp. 255-274
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Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS
Neuron, Vol. 67, Núm. 5, pp. 834-846