LUIS CESAR
FERNANDEZ DIAZ
PROFESOR DOCTOR
Publicaciones (16) Publicaciones de LUIS CESAR FERNANDEZ DIAZ
2020
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Combined MEK and PI3K/p110β inhibition as a novel targeted therapy for malignant mesothelioma displaying sarcomatoid features
Cancer Research, Vol. 80, Núm. 4, pp. 843-856
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Mutations in non-tumoral human urothelium: Disease prelude or epilogue?
Bladder Cancer, Vol. 6, Núm. 3, pp. 249-252
2018
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C-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis
Gut, Vol. 67, Núm. 4, pp. 707-718
2016
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Somatic Embryonic FGFR2 Mutations in Keratinocytic Epidermal Nevi
Journal of Investigative Dermatology, Vol. 136, Núm. 8, pp. 1718-1721
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Somatic mosaicism: On the road to cancer
Nature Reviews Cancer, Vol. 16, Núm. 1, pp. 43-55
2013
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Analysis of the DNA-Binding Profile and Function of TALE Homeoproteins Reveals Their Specialization and Specific Interactions with Hox Genes/Proteins
Cell Reports, Vol. 3, Núm. 4, pp. 1321-1333
2012
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Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein
Stem Cells, Vol. 30, Núm. 11, pp. 2423-2436
2010
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Prep1 (pKnox1)-deficiency leads to spontaneous tumor development in mice and accelerates EμMyc lymphomagenesis: A tumor suppressor role for Prep1
Molecular Oncology, Vol. 4, Núm. 2, pp. 126-134
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The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells
Development, Vol. 137, Núm. 20, pp. 3393-3403
2009
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Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels
Molecular and Cellular Biology, Vol. 29, Núm. 5, pp. 1143-1151
2008
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Oncogenic HoxB7 requires TALE cofactors and is inactivated by a dominant-negative Pbx1 mutant in a cell-specific manner
Cancer Letters, Vol. 266, Núm. 2, pp. 144-155
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Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism
Molecular and Cellular Biology, Vol. 28, Núm. 18, pp. 5634-5645
2006
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Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype
Molecular and Cellular Biology, Vol. 26, Núm. 15, pp. 5650-5662
2005
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Involvement of Prep1 in the αβ T-cell receptor T-lymphocytic potential of hematopoietic precursors
Molecular and Cellular Biology, Vol. 25, Núm. 24, pp. 10768-10781
2001
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Effects of MA 956 superalloy and α-alumina particles on some markers of human osteoblastic cells in primary culture
Journal of Biomedical Materials Research, Vol. 54, Núm. 1, pp. 30-36
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Influence of particle size in the effect of polyethylene on human osteoblastic cells
Biomaterials, Vol. 22, Núm. 8, pp. 755-762