Publications en collaboration avec des chercheurs de Hospital Universitario Virgen del Rocío (25)

2024

  1. Evidence of the association between increased use of direct oral anticoagulants and a reduction in the rate of atrial fibrillation-related stroke and major bleeding at the population level (2012–2019)

    Medicina Clinica, Vol. 162, Núm. 5, pp. 220-227

  2. Mutational landscape of risk variants in comorbid depression and obesity: a next-generation sequencing approach

    Molecular Psychiatry, Vol. 29, Núm. 11, pp. 3553-3566

  3. The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery

    Journal of translational medicine, Vol. 22, Núm. 1, pp. 139

  4. drexml: A command line tool and Python package for drug repurposing

    Computational and Structural Biotechnology Journal, Vol. 23, pp. 1129-1143

2023

  1. An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice

    Antioxidants, Vol. 12, Núm. 1

  2. Cell-Level Pathway Scoring Comparison with a Biologically Constrained Variational Autoencoder

    Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

  3. Crosstalk between Metabolite Production and Signaling Activity in Breast Cancer

    International Journal of Molecular Sciences, Vol. 24, Núm. 8

  4. Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models

    International Journal of Molecular Sciences, Vol. 24, Núm. 19

  5. Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments

    Virology Journal, Vol. 20, Núm. 1

  6. SigPrimedNet: A Signaling-Informed Neural Network for scRNA-seq Annotation of Known and Unknown Cell Types

    Biology, Vol. 12, Núm. 4

2022

  1. Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival

    Viruses, Vol. 14, Núm. 9

  2. Discovering potential interactions between rare diseases and COVID-19 by combining mechanistic models of viral infection with statistical modeling

    Human molecular genetics, Vol. 31, Núm. 12, pp. 2078-2089

  3. Integrating pathway knowledge with deep neural networks to reduce the dimensionality in single-cell RNA-seq data

    BioData Mining, Vol. 15, Núm. 1

  4. Towards a metagenomics machine learning interpretable model for understanding the transition from adenoma to colorectal cancer

    Scientific Reports, Vol. 12, Núm. 1

2021

  1. CSVS, a crowdsourcing database of the Spanish population genetic variability

    Nucleic acids research, Vol. 49, Núm. D1, pp. D1130-D1137

  2. Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data

    Computational and Structural Biotechnology Journal, Vol. 19, pp. 2968-2978

  3. Highly accurate whole-genome imputation of SARS-CoV-2 from partial or low-quality sequences

    GigaScience, Vol. 10, Núm. 12

  4. Mechanistic modeling of the SARS-CoV-2 disease map

    BioData Mining, Vol. 14, Núm. 1

  5. Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients

    Scientific Reports, Vol. 11, Núm. 1

2020

  1. Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection

    Signal Transduction and Targeted Therapy