Pulmonary Rehabilitation in SARS-CoV-2: A Systematic Review and Meta-Analysis of Post-Acute Patients

  1. Reinert, Glenn 12
  2. Müller, Daniel 23
  3. Wagner, Pit 2
  4. Martínez-Pozas, Oliver 4
  5. Cuenca-Záldivar, Juan Nicolás 56
  6. Fernández-Carnero, Josué 47788
  7. Sánchez Romero, Eleuterio A. 7788
  8. Corbellini, Camilo 9
  1. 1 Hopitaux Robert Schuman-Centre Médical Clinique Sainte Marie
  2. 2 Physiotherapy Masters of Science Programme, LUNEX International University of Health, Exercise and Sports
  3. 3 Centre Hospitalier de Luxembourg
    info

    Centre Hospitalier de Luxembourg

    Ciudad de Luxemburgo, Luxemburgo

    ROR https://ror.org/03xq7w797

  4. 4 Universidad Rey Juan Carlos
    info

    Universidad Rey Juan Carlos

    Madrid, España

    ROR https://ror.org/01v5cv687

  5. 5 Instituto de Investigación Sanitaria Puerta de Hierro
    info

    Instituto de Investigación Sanitaria Puerta de Hierro

    Madrid, España

  6. 6 Physical Therapy Unit, Primary Health Care Center “El Abajón”
  7. 7 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

  8. 8 Universidad Europea de Canarias
    info

    Universidad Europea de Canarias

    Orotava, España

    ROR https://ror.org/051xcrt66

  9. 9 Department of Physiotherapy, LUNEX International University of Health, Exercise and Sports
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Revista:
Diagnostics

ISSN: 2075-4418

Año de publicación: 2022

Volumen: 12

Número: 12

Páginas: 3032

Tipo: Revisión

DOI: 10.3390/DIAGNOSTICS12123032 GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Diagnostics

Resumen

Background: Pulmonary Rehabilitation (PR) was initially developed for the management of Chronic Obstructive Pulmonary Disease (COPD) and is now recognized as a core management of COVID-19 patients. This systematic review and meta-analysis examined the efficacy of PR in patients with post-acute COVID-19 infection. Methods: A literature search was conducted in PubMed, the Web of Science (WoS), and the Cochrane Library from their inceptions until October 2022, and randomized controlled trials and observational studies were considered. The outcomes measured included dyspnea, physical function, and quality of life. Results: Eleven studies including 677 participants with post-acute COVID-19 were included in this analysis. From a qualitative point of view and analyzing the studies separately, PR improves dyspnea, physical function, and quality of life in patients with post-acute COVID-19. However, in pooling the data of all the studies, no significant changes pre-postintervention, compared to the control, were found among the experimental studies included in the analysis in any outcome measures, due to the high heterogeneity between the studies, as well as no significant improvements being found in the observational studies. A subgroup analysis revealed significant differences in all the included outcomes. Future studies should include the same scale to assess the actual efficacy of PR. Conclusion: From a qualitative analysis point of view, PR is effective in improving physical function, reducing dyspnea, and improving quality of life in patients with post-acute COVID-19. However, an exploratory meta-analysis was performed to evaluate, by subgroups, the efficacy of PR, and positive results were found in favor of PR.

€ Ver financiación

Información de financiación

Award for Best Research Project in post-COVID-19 sequelae awarded by the Ilustre Colegio Profesional de Fisioterapeutas de la Comunidad de Madrid (Spain), December 2021

Financiadores

  • Ilustre Colegio Profesional de Fisioterapeutas de la Comunidad de Madrid Spain

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