Artritis psoriásica

  1. Villalobos Sánchez, L. 1
  2. Guillén Astete, C. 1
  3. Garrote Corral, S. 1
  4. Terán Tinedo, M.A. 1
  5. Vázquez Díaz, M. 1
  1. 1 Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, España
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2021

Serie: 13

Número: 29

Páginas: 1623-1634

Tipo: Artículo

DOI: 10.1016/J.MED.2021.03.020 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

La artritis psoriásica (Aps) es una artropatía inflamatoria crónica que está asociada con la presencia de psoriasis cutánea y factor reumatoide (FR) usualmente negativo. El desarrollo de esta enfermedad depende de factores genéticos predisponentes, condicionantes inmunológicos que perpetúan el ciclo inflamatorio local y la participación de las vías Th1/Th17, así como de las interleuquinas IL-9, IL-12/23 e IL-17. Si bien una parte de la génesis de la Aps se ha explicado mediante estudios de asociación, el conocimiento de los mecanismos que la hacen posible es actualmente incompleto. No hay pruebas específicas para el diagnóstico. Nos basamos en los criterios de clasificación CASPAR y en el apoyo de técnicas de imagen. En los últimos años ha habido un gran avance en el tratamiento inmunosupresor de la Aps, surgiendo nuevos tratamientos contra diferentes dianas.

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