Numerical modelling of blood clot extraction by aspiration thrombectomy. Evaluation of aspiration catheter geometry

  1. Romero, Gregorio
  2. Pearce, Gillian
  3. Wong, Julian
  4. Talayero, Carlos
  1. 1 Universidad Politécnica de Madrid
    info

    Universidad Politécnica de Madrid

    Madrid, España

    ROR https://ror.org/03n6nwv02

  2. 2 University of Birmingham
    info

    University of Birmingham

    Birmingham, Reino Unido

    ROR https://ror.org/03angcq70

  3. 3 National University Heart Centre Singapore
    info

    National University Heart Centre Singapore

    Singapur, Singapur

    ROR https://ror.org/01vvdem88

Journal:
Journal of Biomechanics

ISSN: 0021-9290

Year of publication: 2019

Volume: 94

Pages: 193-201

Type: Article

DOI: 10.1016/J.JBIOMECH.2019.07.033 GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Journal of Biomechanics

Abstract

Aspiration thrombectomy is one of the most effective systems for blood clot removal and vessel recanalization. We present the results of a study involving the modelling and extraction of blood clots in the arteries of the human body using the following computer tools: Bond-Graph methodology for the fluid domain and Multi-Body Simulation for the mechanical domain. The modelling for the mechanical domain focuses on the clot and the distal end section of an aspiration device. Our final model considers an elastic characterization of the blood clot with progressive detachment from the vessel wall. We conclude that the results of such modelling could potentially improve the effectiveness of blood clot removal by reducing the risk of clot fragmentation. Such modelling could also potentially provide an adjunct technique in improving recanalization of arteries over a range of given parameters (mechanical properties of the vessel, mechanical properties of the blood clot, blood clot length, suction pressure, catheter – clot distance, catheter shape, catheter diameter and vessel occlusion).