Association genetic study within the framework of Zuckerman’s psychobiological personality model

  1. García, L.F. 1
  2. Aluja, A. 3
  3. Fibla, J. 1
  4. García, O. 2
  1. 1 Universidad Autónoma de Madrid
    info

    Universidad Autónoma de Madrid

    Madrid, España

    ROR https://ror.org/01cby8j38

  2. 2 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

  3. 3 Universitat de Lleida
    info

    Universitat de Lleida

    Lleida, España

    ROR https://ror.org/050c3cw24

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Revista:
Personality and Individual Differences

ISSN: 0191-8869

Año de publicación: 2014

Volumen: 60

Páginas: S51

Tipo: Artículo

DOI: 10.1016/J.PAID.2013.07.207 GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Personality and Individual Differences

Resumen

This research explores if some polymorphisms associated to Serotonin (5-HTTLPR and 5-HTTVNTR), Dopamine (DRD2), testosterone (CAG and GGN) and two enzymes (COMT [Val158Met] and MAO-A) may be linked to differences on Impulsive-Sensation Seeking, Neuroticism and Extroversion factors of the Zuckerman’s personality model. Hypothesis reproduce the concrete paths raised by Zuckerman’s Psychobiological model (Zuckerman, 2005) from differences on serotonin, dopamine, testosterone, COMT and MAO-A to differences on personality basic traits. Several phenotypic personality measures (ImpSS, N-Anx, and Sy from the ZKPQ, P from EPQ-R, Barratt’s Impulsivity Scale, and N, E, and C from the NEO-FFI) were applied to two samples: 153 inmates and 105 controls. All males. Results give some support to the Zuckerman’s psychobiological model since phenotypic differences were mostly in the predicted direction when the role of different polymorphisms was considered conjointly.