Protocolo de actuación en implantología oral en pacientes tratados con bifosfonatos intravenosos
- Pablo Atanes Bonome
- Alicia Martín Cerrato
- Antonio De la Plaza Julián
- María Luisa Martínez García
- Rafael Gómez Font
ISSN: 1135-2949
Datum der Publikation: 2013
Nummer: 250
Seiten: 102-117
Art: Artikel
Andere Publikationen in: Gaceta dental: Industria y profesiones
Zusammenfassung
The bisphosphonates are stable inorganic pyrophosphate analogs that have demonstrated their efficacy in treatment of variety of pathologies, such as osteolytic lesions associated with bony metastases or multiple myeloma, malignant hypercalce- mia, Paget ́s disease, and osteoporosis. The main pharmacological effect of bisphosphonates is the inhibition of bone resorption. Several publications within the last years consider osteonecrosis of the maxillary to be associated with bisphosphonate therapy as a result of their extensive use, which is defined as bone avascular necrosis of mutlifactorial etiology. It is important for patients to be informed of the risk of this complication, so that they have the opportunity to assess the need for dental treatment before starting therapy. Preventive measures must be taken before, during, and after treatment with bisphosphonates. Surgical treatment should be reserve for those patients who are symptomatic. The purpose of this study intends to develop a series of preventive and curative protocols and 4 guidelines for action in the treatment of patients with intravenous bisphosphonates undergoing oral surgery implantology.