Reproducibilidad de la medición manual del grosor coroideo utilizando la tomografía de coherencia óptica

  1. M.M. Esteban-Ortega 12
  2. M. Steiner 12
  3. I. García-Lozano 12
  4. I. Thuissard-Vasallo 2
  5. M. Moriche-Carretero 12
  6. S. Munoz-Fernández 12
  1. 1 Hospital Infanta Sofia
    info

    Hospital Infanta Sofia

    Madrid, España

    ROR https://ror.org/05dfzd836

  2. 2 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2020

Volume: 95

Issue: 8

Pages: 379-385

Type: Article

DOI: 10.1016/J.OFTAL.2020.03.013 DIALNET GOOGLE SCHOLAR

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Purpose Spectral-domain optical coherence tomography (SD-OCT) is the most useful tool to measure choroidal thickness (CT). CT may be increased in ocular and systemic diseases. However, there are concerns relating reproducibility and external validity of OCT. The aim of this study was to assess the inter-observer and intra-observer variability of manual OCT measurements. Methods CT was manually measured in the central choroid of 40 eyes from 21 subjects (11 healthy and 10 with ankylosing spondylitis) using RTVue-100 OCT (Optovue Inc., Fremont, CA, EE. UU.). Measurements were performed by 9 independent ophthalmologists from 6 different centers. To assess the inter-observer variability, the intra-class correlation coefficient (ICC) method was calculated. Also, intra-observer variability was assessed in 2 of the ophthalmologists. Results The mean subfoveal CT was 364.9 ± 85.1 μm (range, 170 to 572). The inter-observer ICC was 0.823 (CI 95%, 0.749 to 0.888, p < 0.001). The intra-observer ICCs were 0.885 (CI 95%, 0.783 to 0.939, p < 0.001) and 0.925 (CI 95%, 0.859 to 0.960. p < 0.001). Conclusions In this study, manual measurements of CT with OCT showed a good concordance. These results suggest that manual OCT is a valid tool for multicenter studies.

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Funding information

Al grupo COnTEST formado por M. Muxima Patricia Acebes Garc?a, Cristina del-Prado-Sanchez, David D?az-Valle, Teresa D?az-Valle, Mar?a Carmen Garc?a-Saenz, Maria Gurrea-Almela, Rosal?a Mendez-Fernandez, Eugenio P?rez-Bl?zquez, Bego?a Pastor-Nieto, Javier Sambricio-Garcia, David Sanz-Rosa y Nuria Vald?s-Sanz.

Funders

Data source: Dialnet