Osteonecrosis de los maxilares y anticuerpos monoclonalesuna revisión bibliográfica

  1. Ainara García Gil
  2. Marta Muñoz Corcuera 1
  3. Ignacio García Gil 1
  1. 1 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

Journal:
Científica dental: Revista científica de formación continuada

ISSN: 1697-6398,  1697-641X

Year of publication: 2019

Volume: 16

Issue: 2

Pages: 49-56

Type: Article

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More publications in: Científica dental: Revista científica de formación continuada

Abstract

The aim is establish if there is a scientific evidence to support a relationship between the administration of monoclonal antibodies and the appearance of osteonecrosis of the jaws (ONJ). In the literature we review shows certain cases inwhich ONJ is relatedto monoclonal antibodies (denosumab, sunitib,etc.) as long as the patient undergoes dental treatment Those articles in which monoclonal antibodies and bisphosphonates are administered simultaneously are also evaluated and it is observed that the frequency of ONJ is higher. As conclusión it is established that there is not enough scientific evidence to ensure a relationship between ONJ and monoclonal antibodies, but there is evidence to show that the relationship between ONJ and monoclonal antibodies if administered with bisphosphonates.

Data source: Dialnet