Osteonecrosis de los maxilares y anticuerpos monoclonalesuna revisión bibliográfica
- Ainara García Gil
- Marta Muñoz Corcuera 1
- Ignacio García Gil 1
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1
Universidad Europea de Madrid
info
ISSN: 1697-6398, 1697-641X
Year of publication: 2019
Volume: 16
Issue: 2
Pages: 49-56
Type: Article
More publications in: Científica dental: Revista científica de formación continuada
Abstract
The aim is establish if there is a scientific evidence to support a relationship between the administration of monoclonal antibodies and the appearance of osteonecrosis of the jaws (ONJ). In the literature we review shows certain cases inwhich ONJ is relatedto monoclonal antibodies (denosumab, sunitib,etc.) as long as the patient undergoes dental treatment Those articles in which monoclonal antibodies and bisphosphonates are administered simultaneously are also evaluated and it is observed that the frequency of ONJ is higher. As conclusión it is established that there is not enough scientific evidence to ensure a relationship between ONJ and monoclonal antibodies, but there is evidence to show that the relationship between ONJ and monoclonal antibodies if administered with bisphosphonates.