Replicación inducida por estrés térmico en cromosoma y plásmidos de Escherichia coli

  1. González Soltero, María Rocío
Supervised by:
  1. Alfonso Jiménez Sánchez Director
  2. Emilia Carmen Botello Cambero Director

Defence university: Universidad de Extremadura

Fecha de defensa: 28 March 2007

Committee:
  1. Juan Carlos Alonso Navarro Chair
  2. Luis Miguel Hernández Martín Secretary
  3. José Emilio Rebollo Feria Committee member
  4. Ramón Díaz Oreja Committee member
  5. Fernando Henao Dávila Committee member

Type: Thesis

Teseo: 175501 DIALNET lock_openDialnet editor

Abstract

A temperature upshift of ten or more degrees in the growth temperature of an Escherichia coli culture causes induction of on extra rounds of chromosome replication that are denominated HIR (heat induced replication). In this work we have determined the estructural requirements in DNA and the functions that are needed during the initiation and elongation in HIR. The model that we proposed explains the nature of this replication. Consedering the fact that heat induced replications were also identified in minicromosomes and plasmids, HIR could be a general response to heat stress in the bacterial world.