Evolution of regenerative endodontic in young permanent teeth: a literature review

  1. Jamet, Jean-Hugues 1
  2. Conde, Antonio Jesus 1
  3. De la Hoz, Ana 1
  4. Pérez Alfayate, Ruth 1
  5. Loroño, Gaizka 1
  6. Patrícia Correia Siqueira 2
  7. Estevez, Roberto 1
  1. 1 Universidad Europea de Madrid
    info
    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

    Geographic location of the organization Universidad Europea de Madrid
  2. 2 Universidade Federal de Goiás
    info
    Universidade Federal de Goiás

    Goiânia, Brasil

    ROR https://ror.org/0039d5757

    Geographic location of the organization Universidade Federal de Goiás
Journal:
ROBRAC: Revista Odontológica do Brasil Central

ISSN: 1981-3708,  0104-7914

Year of publication: 2023

Volume: 32

Issue: 91

Pages: 1-32

Type: Article

DOI: 10.36065/ROBRAC.V32I91.1662 GOOGLE SCHOLAR lock_openOpen access editor HANDLE: https://hdl.handle.net/11268/13676

More publications in: ROBRAC: Revista Odontológica do Brasil Central

ABACUS. Repositorio de Producción Científica: lock_openOpen access Handle

Abstract

Objective: to compare different protocols available for regenerative endodon-tic. Methodology: articles published between 2001 and 2021 were searched on the database PubMed using the following keywords: “pulp revascular-ization” or “pulp revitalization” or “apexification”. Inclusion criteria were studies on humans, patients with immature permanent teeth with necrosis or irreversible pulpitis, a follow-up of at least 12 months, clearly described protocols and in English language. Results: The search produced 944 results. After applying the inclusion and exclusion criteria, only 35 were selected. 11 articles were added following a bibliographic review of the selected articles and a total of 46 cases were included. The success rate outcome for regener-ative endodontic was of 80% observed in a total of 278 teeth. During irriga-tion, NaOCL was used in most of the cases with concentration varying from 0.5% to 6% and TAP has been the most used intracanal medication (32.7%). Periapical healing and resolution of the symptoms were observed in 95.7%, while apexogenesis was observed in 80.2%. Increase in root length reach 60%, root thickness 64.8% and apical closure 61,9%. Pulp vitality was found in 7.2% of the cases and discoloration in 29.5%. Conclusion: Regenerative endodontic showed signs of apexogenesis in most cases, and a pronounced increase in root thickness, root length and closure of the apex. Due to a high number of protocols and their heterogenicity, the superiority of one over the others cannot be established. More randomized clinical trials are needed to determine the most effective protoco

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